Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

A Phase II Exploratory Study of SR604 Injection Evaluating the Safety and Efficacy in the Treatment of Congenital Coagulation Factor VII Deficiency Conditions: Factor VII Deficiency Interventions: Drug: SR604 Sponsors: Shanghai RAAS Blood Products Co., Ltd. Not yet recruiting

Pediatric Von Hippel-Lindau Disease: Natural History, Predictive Factors, and Long-Term Functional Outcomes of Central Nervous System Hemangioblastomas Conditions: Von Hippel-Lindau Disease; Central Nervous System Hemangioblastoma Sponsors: Assistance Publique - Hôpitaux de Paris Not yet recruiting

Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome Conditions: Polycystic Ovary Syndrome (PCOS); Myo-inositol; D-chiro-inositol Interventions: Drug: Myo-Inositol and D-Chiro-Inositol Combination Therapy; Drug: placebo (folic acid) Sponsors: Nishtar Medical University Completed

Delayed Versus Immediate Cord Clamping in Preterm Birth Conditions: Preterm Birth Complication; Neonatal Morbidity and Mortality; Cord Clamping; Delayed Cord Clamping; Anemia; NEC - Necrotizing Enterocolitis; Intraventricular Hemorrhage Neonatal; Respiratory Distress Neonatal Interventions: Procedure: Delayed Umbilical Cord Clamping; Procedure: Immediate Umbilical Cord Clamping Sponsors: Faculty of Medicine of Tunis Recruiting

Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haploidentical Hematopoietic Stem Cell Transplantation Conditions: Leukemia; Lymphoma; Thalassemia; Aplastic Anemia; Myelodysplastic Syndromes Interventions: Biological: Intravenous Immunoglobulin; Drug: Dexamethasone; Biological: Mononuclear Cells Sponsors: Hematology department of the 920th hospital Not yet recruiting

TG-INSIGHT With Joint POCUS, Hemostatic Potential in Patients With Severe Hemophilia A on Novel Replacement and Substitution FVIII Therapies Conditions: Hemophilia A; Factor VIII (FVIII) Interventions: Drug: Half-life factor VIII based replacement therapy; Drug: Non-FVIII based replacement therapy Sponsors: University of Texas Southwestern Medical Center; Sanofi Not yet recruiting

High-Flow Nasal Cannula Versus Nasal CPAP as Primary Support in Preterm Respiratory Distress Syndrome Conditions: Premature Birth; Respiratory Distress Syndrome, Newborn Interventions: Device: Group 1 Heated humidified high-flow nasal cannula (HHHFNC); Device: Group 2 Nasal continuous positive airway pressure (nCPAP) Sponsors: Kayseri City Hospital Completed

Effect of Non-Surgical Periodontal Treatment on Oral Health in Hemophilia Patients Conditions: Hemophilia A and B; Periodontitis; Hemophilia Interventions: Procedure: Non-surgical periodontal treatment Sponsors: Karadeniz Technical University Completed

Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) as Prophylactic Treatment. Conditions: Severe Hemophilia A Interventions: Drug: FRSW107 Sponsors: Hangzhou Gensciences Biopharmaceutical Co., Ltd. Recruiting

Multimodal Telerehabilitation Versus Face-to-Face Care for Adults With Hemophilia and Chronic Pain Conditions: Hemophilia; Chronic Pain Interventions: Behavioral: other; Other: Exercise Sponsors: University of Chile Recruiting

LATE-ONSET POMPE DISEASE AND CEREBROVASCULAR MANIFESTATIONS Conditions: Late-Onset Pompe Disease Sponsors: Hospitales Universitarios Virgen del Rocío; Sanofi Completed