Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

Validity and Reliability of the Figure-of-Eight Walking and Weight-Bearing Lunge Tests in Hemophilia Conditions: Hemophilia Sponsors: Yuzuncu Yil University Recruiting

Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder Conditions: Familial Platelet Disorder With Associated Myeloid Malignancy Interventions: Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Other: Questionnaire Administration; Drug: Sirolimus Sponsors: OHSU Knight Cancer Institute; National Cancer Institute (NCI); Oregon Health and Science University; M.D. Anderson Cancer Center Recruiting

Early Postoperative Triple Targeted Therapy in Patients With CHD-PAH in the "Grey Zone" Conditions: Congenital Heart Disease, Pulmonary Hypertension Interventions: Drug: Control group (ambrisentan plus tadalafil or macitentan plus tadalafil); Drug: Treatment group (ambrisentan plus tadalafil plus treprostinil or macitentan plus tadalafil plus treprostinil) Sponsors: China National Center for Cardiovascular Diseases Completed

Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical Hernia Conditions: Umbilical Hernia Repair Interventions: Drug: Topical Tranexamic Acid Spray; Drug: No Topical Tranexamic acid Sponsors: Dr Mudassar Saeed Pansota Not yet recruiting

Prospective Evaluation of iCam-OCT Conditions: Retinopathy of Prematurity Interventions: Device: imaged with i-Cam OCT Sponsors: Siloam Vision; Oregon Health and Science University; Children's Hospital Colorado Completed

Clinical Trial of NXT007 for the Prophylactic Treatment of Hemophilia A in Infants and Children Conditions: Hemophilia A Interventions: Drug: NXT007 Sponsors: Hoffmann-La Roche; Chugai Pharmaceutical Not yet recruiting

Frontal Reconstruction Without Orbital Advancement for Moderate Metopic Craniosynostosis Conditions: Metopic Craniosynostosis; Craniosynostosis; Metopic Synostosis Interventions: Procedure: Frontal vault remodelling without orbital advancement Sponsors: Assiut University Not yet recruiting

Noninvasive High Frequency Oscillatory Ventilation Versus Nasal Intermittent Mandatory Ventilation for Respiratory Distress Syndrome in Preterm Neonates Conditions: Respiratory Distress Syndrome (RDS); Newborn; Premature Birth Interventions: Device: Noninvasive High Frequency Oscillatory Ventilation; Device: Nasal Intermittent Mandatory Ventilation Sponsors: Aga Khan University Not yet recruiting

A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A Conditions: Haemophilia A Interventions: Drug: Denecimig Sponsors: Novo Nordisk A/S Not yet recruiting

Efanesoctocog Prophylaxis Or The Optimization Of Treatment: Real-World Experience Of Taylorizing Clotting Therapy In Hemophilia A Conditions: Hemophilia A Patient Interventions: Other: Study questionnaires; Other: Clinical/pharmacological data collection Sponsors: Nantes University Hospital Not yet recruiting

Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive Crisis Conditions: Sickle Cell Disease; Vaso-occlusive Crisis Interventions: Drug: Group 02 Paracetamol + Morphine + Ketamine; Drug: Group 01 Control: Paracetamol + Morphine; Drug: Group 03 : Paracetamol + Morphine + Nefopam; Drug: Group 04 : Paracetamol + Morphine + Nefopam + Ketamine; Drug: Goup 05 : Paracetamol + Morphine + Tramadol; Drug: Group 6 : Paracetamol + Morphine + Tramadol + Ketamine; Drug: Group 7 : Paracetamol + Morphine + Ketoprofen; Drug: Group 08 : Paracetamol + Morphine + Ketoprofen + Ketamine Sponsors: Assistance Publique - Hôpitaux de Paris Not yet recruiting