Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

IV Bevacizumab Treatment of Patients With Hereditary Hemorrhagic Telangiectasia (HHT) or Rendu-Osler (RO) Disease: A Retrospective Analysis of French Cohort Data From 2009 to 2024 Conditions: Hereditary Hemorrhagic Telangiectasia (HHT); Rendu Osler Disease Interventions: Other: Real World data study. Sponsors: Hospices Civils de Lyon Completed

Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants Conditions: Bronchopulmonary Dysplasia Sponsors: Medical University of Vienna Not yet recruiting

Localized Evidence of Cytokine Adsorption Therapy During Pediatric Cardiac Surgery: A Single Center Randomized Controlled Trial (LEAT) Conditions: Congenital Heart Disease; Open Heart Surgery; Cardiopulmonary Bypass; Endocarditis Acute and Subacute; Cyanotic Heart Disease Interventions: Device: Hemoadsorption (Jafron HA-60/HA380) Sponsors: Norfaniza Zabidi Not yet recruiting

A Study of Clinical Practice and Real-world Care of Patients Treated With mTOR, PI3K, and MEK Inhibitors for Extracranial Vascular Anomalies Conditions: Vascular Anomalies Sponsors: Novartis Pharmaceuticals Not yet recruiting

Higher-Dose Dexamethasone Improves Breathing and Shortens NICU Stay in Preterm Babies Conditions: Premature Birth; Neonatal Hypoglycemia; Maternal Infection During Pregnancy; Neurodevelopmental Disorder of Foetus; Respiratory Distress Syndrome (RDS); Necrotizing Enterocolitis (NEC); Intraventricular Hemorrhage Neonatal; Neonatal Sepsis; Intraventricular Hemorrhage (IVH); Neonatal Respiratory Distress Syndrome Interventions: Drug: Dexamethasone 12 mg Every 12 Hours; Drug: Dexamethasone 6 mg Every 12 Hours Sponsors: Stella Maris Women and Children Hospital; Universitas Sumatera Utara Completed

Liver and Coagulation Disorders in Cardiac Transthyretin Amyloidosis Conditions: Transthyretin (TTR) Amyloid Cardiomyopathy; Cardiac Amyloidosis; Cardiomyopathies; Wild-Type Transthyretin Cardiac Amyloidosis; Hereditary Transthyretin Amyloidosis (ATTRv) Sponsors: University of Messina; Azienda Ospedaliera Universitaria Policlinico "G. Martino" Recruiting

Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease Conditions: Periodontal Disease; Gingivitis and Periodontal Diseases; Biomarker Discovery and Validation; Pathways Interventions: Diagnostic Test: ELISA Biomarker Analysis Sponsors: Inonu University; Harvard University; University of Minnesota Completed

The NEU - CAP Trial Conditions: Infant, Premature, Diseases; Birth, Preterm; Respiratory Distress Neonatal Interventions: Procedure: Local standard care of monitoring non-invasive ventilation; Procedure: CO₂-guided Non-Invasive Ventilation Sponsors: Leiden University Medical Center Not yet recruiting