Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

Wide Field OCTA in Ocular Diseases Conditions: Age - Related Macular Degeneration (AMD); Diabetic Macular Edema; Diabetic Retinopathy; Myopia; Inherited Retinal Disease; Stargardt Disease; Retinitis Pigmentosa (RP); Best Disease; Geographic Atrophy; Macular Neovascularisation; Ocular Surface Disease; Central Serous Choroidopathy; Pachychoroid Disease; Uveitis; Vitreoretinal Disease; Retinal Vein Occlusion Sponsors: IRCCS San Raffaele Not yet recruiting

A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study) Conditions: Breast Cancer; BRCA 1 Gene Mutation; BRCA 2 Gene Mutation; Hereditary Breast Carcinoma; Breast Neoplasms; DCIS; Germline Mutation Abnormality; Early Breast Cancer Interventions: Procedure: Endoscopic nipple sparing mastectomy; Device: HandX endoscopic instrument Sponsors: Vasileios Kalles Recruiting

A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B Conditions: Hemophilia Interventions: Drug: Fitusiran; Biological: Clotting factor concentrates (CFC) or bypassing agents (BPA); Biological: Antithrombin concentrate (ATIIIC) Sponsors: Sanofi Not yet recruiting

Comparison of Analgesic Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Block in Pediatric Patients Undergoing Hypospadias Surgery Conditions: Hypospadias Interventions: Procedure: Caudal Block Anesthesia; Procedure: Erector Spinae Plane Block Sponsors: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Completed

A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome Conditions: Venous Malformations; Lymphatic Malformations; Klippel-Trenaunay Syndrome; CLOVES Syndrome Interventions: Drug: KP-001; Drug: Placebo Sponsors: Kaken Pharmaceutical Not yet recruiting

LATA-IBD TRIAL a Controlled Feasibility Study for the Introduction of Transanal Minimally Invasive IPAA-Surgery. Evaluation of Operative Results and Bowel Function After Introducing Transanal IPAA-surgery to Replace Conventional Laparoscopic IPAA-surgery. Conditions: Ulcerative Colitis (Disorder); Familial Adenomatous Polyposis (FAP) Sponsors: Sahlgrenska University Hospital Completed

Treatment of Moderate-to-Severe Atopic Dermatitis With Ivarmacitinib in Adolescents and Adults Conditions: Atopic Dermatitis (AD) Interventions: Drug: Ivarmacitinib Sulfate Tablets Sponsors: Xiangya Hospital of Central South University Not yet recruiting

Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates Conditions: Preterm Less Than 32wks With IVH, WMI/PVL; Late Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE Interventions: Other: Prospective Clinical and Neurodevelopmental Data Collection Sponsors: Brigham and Women's Hospital; Boston Children's Hospital Recruiting