Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

COL4A1COL4A2: Study of Pathological Conditions Involving Multiple Organs Caused by Mutations in the COL4A1 and COL4A2 Genes Conditions: COL4A1\2; COL4A1-Related Brain Small Vessel Disease With Haemorrhage Interventions: Diagnostic Test: Ophtalmological and cardiological screening Sponsors: Meyer Children's Hospital IRCCS Recruiting

A Multi-center Quasi-experimental Study in Northern Italy to Evaluate the Impact of Sepsis Bundle in Obstetric Settings: the SOS Study Conditions: Sepsis Newborn; Sepsis Interventions: Other: microbiological results from blood cultures or other materials. Sponsors: Fondazione IRCCS Policlinico San Matteo di Pavia Completed

Single-Needle Distal Return for Long-Term Arteriovenous Fistula Care Conditions: Hemodialysis Access; Arteriovenous Fistula; Arteriovenous Fistula Cannulation; Vascular Access; Vascular Access Complication Interventions: Procedure: Single-Needle Distal Return (SNDR) Cannulation; Procedure: Standard Two-Needle AVF Cannulation Sponsors: Suzhou Municipal Hospital of Anhui Province Recruiting

Application of Quantitative Hemorrhage Detection in Fetomaternal Hemorrhage Syndrome for the Diagnosis of Hemolytic Disease of the Newborn Conditions: Hemolytic Disease of the Newborn Sponsors: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Not yet recruiting

Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF) Conditions: Congenital Heart Disease; Unfractionated Heparin; Anti Xa Activity Interventions: Procedure: blood sampling for measuring anti-Xa activity; Procedure: measurement of anti-XA activity Sponsors: Centre Hospitalier Universitaire de la Réunion Not yet recruiting

Analysis of the Therapeutic and Clinical Profile of Cannabinoid Treatments: A Real-World Study Conditions: Chronic Pain; Depression Disorders; Anxiety Disorders; Quality of Life; Cannabidiol Effects; Cannabinoids Interventions: Other: Participants are followed while using cannabis-based products (such as CBD or THC oils, extracts, or isolates) as prescribed by their own physicians for therapeutic purposes. Sponsors: Santa Catarina Federal University; HempMeds Brasil Not yet recruiting

Evaluation of Albumin Platelet-Rich Fibrin Following SRP in Patients With Periodontitis Conditions: Periodontitis; Periodontitis (Stage 3) Interventions: Procedure: Albumin platelet-rich fibrin; Other: Sterile saline (0.9%) Sponsors: Saglik Bilimleri Universitesi; The Scientific and Technological Research Council of Turkey Active, not recruiting

Endothelial Colony-Forming Cells in Patients With VWD, AVWS and Healthy Subjects Conditions: Von Willebrand Disease (VWD); Acquired Von Willebrand Disease Interventions: Diagnostic Test: Blood sample collection for VWF measurements in plasma; Other: Blood sample collection for ECFC isolation and characterization; Other: Genetic testing of VWF Sponsors: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Recruiting

A Study of Sotatercept for Patients With Eisenmenger Syndrome or Unrepaired Shunt-Associated Pulmonary Arterial Hypertension Resistant to Vasodilator Therapy Conditions: Eisenmenger Syndrome; Pulmonary Arterial Hypertension of Congenital Heart Disease Interventions: Drug: Sotatercept; Drug: vasodilator-based PAH therapy Sponsors: Kazuya Hosokawa Recruiting

Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis Conditions: Cerebral Arteriovenous Malformation; Intracranial Arterial Diseases; Intra Cerebral Hemorrhage; Intracranial Aneurysm; Brain Diseases Sponsors: Duan Chuanzhi; Beijing Tiantan Hospital; The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Nanchang University; Second Affiliated Hospital of Nanchang University; Shenzhen Second People's Hospital; Guangdong 999 Brain Hospital Not yet recruiting

A Clinical Study to Assess Sutacimig in Participants With Congenital Factor VII Deficiency Conditions: Congenital Factor VII Deficiency Interventions: Drug: Sutacimig; Drug: Sutacimig Sponsors: Hemab ApS Recruiting

Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA Conditions: Total Colonic Aganglionosis; Hirschsprung Disease; Duhamel; Soave Interventions: Procedure: Transanal Transection Duhamel operation; Procedure: Modified Soave Pull-Through Sponsors: Zunyi Medical College; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; The First Affiliated Hospital of Zhengzhou University; Shenzhen Longhua District Maternity and Child Healthcare Hospital; The Affiliated Hospital of Binzhou Medical College; Guizhou Provincial People's Hospital Not yet recruiting