Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

Retinopathy of Prematurity - Visual Function and Retinal Structure Conditions: Retinopathy of Prematurity (ROP); Prematurity Complications; Cerebral Visual Impairment; Visual Field Defect Sponsors: Oslo University Hospital Not yet recruiting

Validity and Reliability of the Two-minute Step Test in Hemophilia Conditions: Hemophilia; Step; Reliability and Validity Sponsors: Hasan Kalyoncu University Not yet recruiting

Non-Inferiority Test of Mixsafe® Compared to Neopuff® in Providing Respiratory Support to Neonates Conditions: Respiratory Distress Syndrome, Newborn; Neonatal Respiratory Disorders Interventions: Device: Mixsafe T piece resucitator; Device: Standardized T Piece resuscitator Sponsors: Dr Cipto Mangunkusumo General Hospital Completed

Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy Conditions: Hemophilia Interventions: Other: Educational group Sponsors: Investigación en Hemofilia y Fisioterapia Not yet recruiting

Incidence of Ultrasonographically Detected Articular Damage in Initially Healthy Joints of Patients With Hemophilia A Receiving Prophylactic Treatment With Emicizumab Conditions: Hemophilia Interventions: Other: Hemophilia patients Sponsors: Investigación en Hemofilia y Fisioterapia Not yet recruiting

Study of a Smart Sharps Disposal Device in Patients With Hemophilia Conditions: Hemophilia A and B Interventions: Other: The smart Sharps device is given to the patient and they use it to throw needles away in. It is not internal to the patient. Sponsors: University of Pennsylvania; Sharpscue Not yet recruiting

External Multicenter Validation of the APTTO Model for Prolonged APTT Using Clot Waveform Analysis Conditions: Coagulation Disorder, Blood; Prolonged APTT Interventions: Other: Clot waveform analysis-based risk stratification (APTTO models) Sponsors: Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A Conditions: Hemophilia A Interventions: Combination Product: NXT007; Drug: Human Coagulation Factor VIII Sponsors: Hoffmann-La Roche; Chugai Pharmaceutical Not yet recruiting

Determinants and Consequences of the Transition to Adulthood for Adolescents With Severe Haemophilia: TRANSHEMO 2, an Ancillary Study to the TRANSHEMO Project Conditions: Haemophilia Interventions: Other: questionnaires Sponsors: Assistance Publique Hopitaux De Marseille Not yet recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A Conditions: Hemophilia A Interventions: Combination Product: NXT007; Drug: Emicizumab Sponsors: Hoffmann-La Roche; Chugai Pharmaceutical Not yet recruiting

Hemophilia A Research Program Conditions: Hemophilia A; Hemophilia A, Severe; Factor VIII (FVIII); FVIII Deficiency; Carrier of Hemophilia A; Inhibitors; Pregnancy; Maternal Blood Loss; Pregnancy Complications; Bleeding Disorder; Hemorrhage, Postpartum; Alloimmunization; X-Linked Sponsors: University of Washington; National Heart, Lung, and Blood Institute (NHLBI); RTI International; Emory University Recruiting

Clinical Spectrum and Management of Von Willebrand Disease Among Children in Assiut Governorate Conditions: Von Willebrand Disease (VWD); Inherited Bleeding Disorders in Children; Pediatric Hemostatic Disorders Interventions: Drug: Tranexamic Acid; Drug: Von Willebrand Factor-Containing Concentrates Sponsors: Assiut University Not yet recruiting

Ex Vivo Reproduction of Minimally Invasive Surgery With Hematoma Lysis Using Modified Tissue Plasminogen Activator for Intracerebral Hemorrhage Conditions: Intracerebral Hemorrhage; Hemorrhagic Risk Conditions; Bleeding Disorders Interventions: Other: Ex vivo exposure to modified rtPA Sponsors: University Hospital, Lille Not yet recruiting

PCC Treatment for Hemophilia Patients With Inhibitor（2022PCC-A） Conditions: Hemophilia; Inhibitors Interventions: Drug: PCC Sponsors: Institute of Hematology & Blood Diseases Hospital, China; North China University of Science and Technology; The Second Affiliated Hospital of Kunming Medical University; The Second People's Hospital of Anhui Province; Children's Hospital of Chongqing Medical University; Union Hospital, Affiliated to Fujian Medical University; The First Affiliated Hospital of Xiamen University; First Affiliated Hospital of Guangxi Medical University Recruiting

Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety Conditions: Venous Malformations; Arteriovenous Malformations; Microwave Ablation; Vascular Malformations Interventions: Device: Microwave Ablation Sponsors: Chengdu University of Traditional Chinese Medicine Not yet recruiting

An Observational Study of Vonicog Alfa (rVWF) in Pediatric Participants With Von Willebrand Disease (vWD) Conditions: Von Willebrand Disease (vWD) Interventions: Drug: vonicog alfa (rVWF) Sponsors: Takeda Recruiting