Clinical Trials

Below is a list of active clinical trials worldwide which involve patients with inherited bleeding disorders. The link from each study title will take you to ClinicalTrials.gov which gives you more information about the trial.
To see a list of trials for a particular bleeding disorder use the drop-down list below to select the condition you're interested in. A new window will open up with a list of trials for this condition only.

Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE) Conditions: Periodontal Disease; Periodontitis; CKD; Chronic Kidney Disease; Alport Syndrome; Fabry Disease; Lupus or SLE; Tuberous Sclerosis Complex (TSC); Systemic Lupus Erythematosus (SLE) Interventions: Other: Observational assessment Sponsors: Stefan Lujinschi; Institutul Clinic Fundeni Not yet recruiting

HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB Conditions: Von Willebrand Disease (VWD); Heavy Menstrual Bleeding (HMB) Interventions: Drug: ALN-6400 Sponsors: Alnylam Pharmaceuticals Not yet recruiting

North American Fetal Therapy Network Prospective Registry for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia Conditions: Congenital Diaphragmatic Hernia Interventions: Device: Fetoscopic Endoluminal Tracheal Occlusion; Other: Standard of Care Sponsors: Mayo Clinic Not yet recruiting

Comparison of Surgical Blade No. 11 and Ophthalmic Knife in Idiopathic Clubfoot Patients Conditions: Clubfoot Interventions: Device: Surgical Blade; Device: Ophthalmic Knife Sponsors: Muhammad Aamir Latif Recruiting

Percutaneous Achilles Tendon Tenotomy vs Tendo-Achilles Lengthening (TAL) in Neglected Clubfoot Children. Conditions: Clubfoot Interventions: Procedure: Tenotomy of Achilles Tendon; Procedure: Tendo-Achilles Lengthening Sponsors: Muhammad Aamir Latif Recruiting

Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below Conditions: Bronchopulmonary Dysplasia Interventions: Drug: intravenous immunoglobulin Sponsors: International Peace Maternity and Child Health Hospital Recruiting

Effect of Apiban Therapy on AVF Maturation in ESRD Patients Conditions: Endstage Renal Disease; Direct Oral Anticoagulants (DOACs); Arteriovenous Fistula; Arteriovenous Fistula Occlusion Interventions: Drug: Apixaban Sponsors: Combined military hospital lahore Recruiting

The Bleeding Assessment Tool (BAT) Conditions: Bleeding Disorder; Von Willebrand Disease (VWD) Sponsors: Children's Hospital Medical Center, Cincinnati Active, not recruiting

Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR) Conditions: Fetal Growth Restriction (FGR) Interventions: Drug: Melatonin; Drug: Placebo Sponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Enrolling by invitation

Efficacy and Safety of Switching to Ivarmacitinib in Patients With Moderate-to-Severe Atopic Dermatitis With Inadequate Response to Interleukin-4 Receptor Alpha(IL-4Rα) Inhibitors: A Prospective, Multicenter, Real-World Study Conditions: Atopic Dermatitis (AD) Interventions: Drug: Ivarmacitinib Sulfate Tablets Sponsors: Peking University People's Hospital Not yet recruiting

a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues Conditions: Maxillofacial Deformity; Maxillofacial Abnormalities; Maxillo-facial Surgery Interventions: Procedure: conventional le fort I osteotomy type; Procedure: subspinal le fort I osteotomy type Sponsors: TC Erciyes University Completed